MS Access 2010 provides a Trusted Locations feature, described by Microsoft as follows:
“If you want to differentiate safe files from potentially harmful files, you can use the Trusted Locations feature in Microsoft Office 2010. The Trusted Locations feature lets you designate trusted file sources on the hard disks of users' computers or on a network share. When a folder is designated as a trusted file source, any file that is saved in the folder is assumed to be a trusted file. When a trusted file is opened, all content in the file is enabled and active, and users are not notified about any potential risks that might be contained in the file, such as unsigned add-ins and Microsoft Visual Basic for Applications (VBA) macros, links to content on the Internet, or database connections”.
“Both user-defined and policy-defined trusted locations can be used”.